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Non-active antibiotic and bacteriophage synergism to successfully treat recurrent urinary tract infection caused by extensively drug-resistant Klebsiella pneumoniae

We report a case of a 63-year-old female patient who developed a recurrent urinary tract infection (UTI) with extensively drug-resistant Klebsiella pneumoniae (ERKp). In the initial two rounds of phage therapy, phage resistant mutants developed within days. Although ERKp strains were completely resi...

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Principais autores: Juan Bao, Nannan Wu, Yigang Zeng, Liguang Chen, Linlin Li, Lan Yang, Yiyuan Zhang, Mingquan Guo, Lisha Li, Jie Li, Demeng Tan, Mengjun Cheng, Jingmin Gu, Jinghong Qin, Jiazheng Liu, Shiru Li, Guangqiang Pan, Xin Jin, Bangxin Yao, Xiaokui Guo, Tongyu Zhu, Shuai Le
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2020-01-01
Colecção:Emerging Microbes and Infections
Assuntos:
Bacteriophage
phage therapy
antibiotic resistance
urinary tract infection
Acesso em linha:https://www.tandfonline.com/doi/10.1080/22221751.2020.1747950
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