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A Novel Approach to the Synthesis of 1,3,4-Thiadiazole-2-amine Derivatives

The main purpose of the study was the development of a new method for synthesis of 1,3,4-thiadiazol-2-amine derivatives in a one-pot manner using the reaction between a thiosemicarbazide and carboxylic acid without toxic additives such as POCl<sub>3</sub> or SOCl<sub>2</sub>. The reaction was invest...

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Principais autores: Tatiana S. Kokovina, Svyatoslav Y. Gadomsky, Alexei A. Terentiev, Nataliya A. Sanina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-08-01
Serier:Molecules
Fag:
1,3,4-thiadiazole-2-amine
thiadiazoles
polyphosphate ester
cyclodehydration reaction
one-pot synthesis
Online adgang:https://www.mdpi.com/1420-3049/26/17/5159
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