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Methotrexate-induced Pancytopenia in Two Patients with Renal Dysfunction

Methotrexate (MTX) is cleared primarily by renal excretion. The excretion of MTX is delayed in subjects with renal dysfunction and elevated plasma MTX concentrations develop which lead to bone marrow toxicities and possible pancytopenia. In this case report, we presented two advanced age patients wi...

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Principais autores: Yusuf OĞUZ, Tayfun EYİLETEN, Murat KARAMAN, Seyid Ahmet AY, Mahmut İlker YILMAZ
Format: Artigo
Sprog:Inglês
Udgivet: Turkish Society of Nephrology 2019-02-01
Serier:Turkish Journal of Nephrology
Fag:
Methotrexate
Toxicity
Pancytopenia
Renal failure
Haemodialysis
Online adgang:https://turkjnephrol.org/index.php/pub/article/view/738
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