Sustained store-operated calcium entry utilizing activated chromatin state leads to instability in iTregs

Thymus-originated tTregs and in vitro induced iTregs are subsets of regulatory T cells. While they share the capacity of immune suppression, their stabilities are different, with iTregs losing their phenotype upon stimulation or under inflammatory milieu. Epigenetic differences, particularly methyla...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Huiyun Lyu, Guohua Yuan, Xinyi Liu, Xiaobo Wang, Shuang Geng, Tie Xia, Xuyu Zhou, Yinqing Li, Xiaoyu Hu, Yan Shi
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	eLife Sciences Publications Ltd 2023-12-01
Σειρά:	eLife
Θέματα:	Treg stability calcium signal NFAT chromatin accessibility iTreg
Διαθέσιμο Online:	https://elifesciences.org/articles/88874
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