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Computational completion of the Aurora interaction region of N-Myc in the Aurora a kinase complex

Abstract Inhibiting protein–protein interactions of the Myc family is a viable pharmacological strategy for modulation of the levels of Myc oncoproteins in cancer. Aurora A kinase (AurA) and N-Myc interaction is one of the most attractive targets of this strategy because formation of this complex bl...

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Autores principales: Pinar Altiner, Süleyman Selim Çınaroğlu, Ahmet Can Timucin, Emel Timucin
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2023-10-01
Colección:Scientific Reports
Acceso en línea:https://doi.org/10.1038/s41598-023-45272-3
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