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A topology-preserving dimensionality reduction method for single-cell RNA-seq data using graph autoencoder

Abstract Dimensionality reduction is crucial for the visualization and interpretation of the high-dimensional single-cell RNA sequencing (scRNA-seq) data. However, preserving topological structure among cells to low dimensional space remains a challenge. Here, we present the single-cell graph autoen...

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Váldodahkkit: Zixiang Luo, Chenyu Xu, Zhen Zhang, Wenfei Jin
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2021-10-01
Ráidu:Scientific Reports
Liŋkkat:https://doi.org/10.1038/s41598-021-99003-7
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