Ameliorative Role of a Plant-based Decoction in Streptozotocin-induced β-cell Damage: Targeting Oxidative Stress and the Nucleotide-binding Domain Leucine-rich Receptor, the Pyrin Domain Containing 3/Thioredoxin-interacting Protein Pathway

Objective: Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder characterized by insulin resistance, β-cell dysfunction, oxidative stress, and chronic inflammation. Oxidative stress activates thioredoxin-interacting protein (TXNIP), which activates the nucleotide-binding domain leucine-ri...

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Auteurs principaux:	Komal Chaudhry, Hafiz Muhammad Irfan, Muhammad Omer, Faiqa Chaudhry
Format:	Artigo
Langue:	Inglês
Publié:	Wolters Kluwer Medknow Publications 2026-01-01
Collection:	World Journal of Traditional Chinese Medicine
Sujets:	botanical mixture nlrp3 streptozotocin thioredoxin-interacting protein type 2 diabetes mellitus
Accès en ligne:	https://journals.lww.com/10.4103/wjtcm.wjtcm_63_25
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