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Qiangjing tablets ameliorate asthenozoospermia via mitochondrial ubiquitination and mitophagy mediated by LKB1/AMPK/ULK1 signaling

AbstractContext Therapeutic effects of Qiangjing tablets (QJT) on sperm vitality and asthenozoospermia (AZS) have been confirmed. However, the mechanism of action remains unclear.Objective This study investigates the effects of QJT on AZS and the underlying mechanism of action.Materials and methods...

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Principais autores: Guangsen Li, Yuanjie Xu, Yingxi Li, Degui Chang, Peihai Zhang, Ziyang Ma, Di’ang Chen, Yaodong You, Xiaopeng Huang, Jian Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2023-12-01
coleção:Pharmaceutical Biology
Assuntos:
Mitophagy
LKB1/AMPK/ULK1
sperm motility
mitochondria
traditional Chinese medicine
Acesso em linha:https://www.tandfonline.com/doi/10.1080/13880209.2023.2168021
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