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Regulation and Functions of 15-Lipoxygenases in Human Macrophages

Lipoxygenases (LOXs) catalyze the stereo-specific peroxidation of polyunsaturated fatty acids (PUFAs) to their corresponding hydroperoxy derivatives. Human macrophages express two arachidonic acid (AA) 15-lipoxygenating enzymes classified as ALOX15 and ALOX15B. ALOX15, which was first described in 1...

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Autori principali: Ryan G. Snodgrass, Bernhard Brüne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-07-01
Serie:Frontiers in Pharmacology
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Accesso online:https://www.frontiersin.org/article/10.3389/fphar.2019.00719/full
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