Hepatitis C virus NS5A protein promotes the lysosomal degradation of diacylglycerol O-acyltransferase 1 (DGAT1) via endosomal microautophagy

Many viruses often use a protein degradation system (e.g., the ubiquitin-proteasome pathway or lysosome pathway) to modulate viral propagation and viral pathogenesis. We reported that hepatitis C virus (HCV) infection promotes the lysosomal degradation of hepatocyte nuclear factor-1α (HNF-1α) via ch...

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Autors principals:	Putu Yuliandari, Chieko Matsui, Lin Deng, Takayuki Abe, Hiroyuki Mori, Shuhei Taguwa, Chikako Ono, Takasuke Fukuhara, Yoshiharu Matsuura, Ikuo Shoji
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2022-12-01
Col·lecció:	Autophagy Reports
Matèries:	dgat1 emi endosomal microautophagy hepatitis c virus lysosomal degradation ns5a
Accés en línia:	http://dx.doi.org/10.1080/27694127.2022.2095591
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