Characterization of two distinct immortalized endothelial cell lines, EA.hy926 and HMEC-1, for in vitro studies: exploring the impact of calcium electroporation, Ca2+ signaling and transcriptomic profiles

Abstract Background Disruption of Ca2+ homeostasis after calcium electroporation (CaEP) in tumors has been shown to elicit an enhanced antitumor effect with varying impacts on healthy tissue, such as endothelium. Therefore, our study aimed to determine differences in Ca2+ kinetics and gene expressio...

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Detalhes bibliográficos

Principais autores:	Barbara Lisec, Tim Bozic, Iva Santek, Bostjan Markelc, Milka Vrecl, Robert Frangez, Maja Cemazar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-02-01
Colecção:	Cell Communication and Signaling
Assuntos:	Endothelial cells Calcium electroporation Calcium kinetics Transcriptomic profiling
Acesso em linha:	https://doi.org/10.1186/s12964-024-01503-2
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