Identification of a Classical Mutant in the Industrial Host Aspergillus niger by Systems Genetics: LaeA Is Required for Citric Acid Production and Regulates the Formation of Some Secondary Metabolites

The asexual filamentous fungus Aspergillus niger is an important industrial cell factory for citric acid production. In this study, we genetically characterized a UV-generated A. niger mutant that was originally isolated as a nonacidifying mutant, which is a desirable trait for industrial enzyme pro...

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Hlavní autoři:	Jing Niu, Mark Arentshorst, P. Deepa S. Nair, Ziyu Dai, Scott E. Baker, Jens C. Frisvad, Kristian F. Nielsen, Peter J. Punt, Arthur F.J. Ram
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2016-01-01
Edice:	G3: Genes, Genomes, Genetics
Témata:	organic acids filamentous fungi bulk segregant analysis parasexual cycle genome sequencing
On-line přístup:	http://g3journal.org/lookup/doi/10.1534/g3.115.024067
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