Ultrasound-responsive nanodroplets activate the Hippo pathway via ROS-MST1-YAP cascade for breast cancer therapy

Dysregulated Hippo signaling critically promotes malignant proliferation, invasion and distant metastasis across multiple cancers, while precise and coordinated modulation of this core pathway remains a major unmet therapeutic hurdle in clinical cancer treatment. Here, we report for the first time t...

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Detalhes bibliográficos

Principais autores:	Yuye Fu, Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Xiaoxuan Wang, Rui Liu, Shuting Huang, Xiaoyue Zhang, Jie Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-08-01
coleção:	Ultrasonics Sonochemistry
Assuntos:	Hippo Nanodroplet Ultrasound-targeted microbubble destruction Reactive oxygen species YAP Triple-negative breast cancer
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1350417726002142
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