Identification of Amino Acid Residues in Angiotensin II Type 1 Receptor Sensing Mechanical Stretch and Function in Cardiomyocyte Hypertrophy

Background/Aims: Angiotensin II (AngII) type 1 receptor (AT1R) could be activated by mechanical stress without the involvement of AngII during the development of cardiac hypertrophy. We aimed to identify sensing sites of AT1R for activation by mechanical stretch. Methods: We constructed several site...

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Detalhes bibliográficos

Principais autores:	Guoliang Jiang, Hui Gong, Yuhong Niu, Chunjie Yang, Shijun Wang, Zhidan Chen, Yong Ye, Ning Zhou, Guoping Zhang, Junbo Ge, Yunzeng Zou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cell Physiol Biochem Press GmbH & Co KG 2015-08-01
coleção:	Cellular Physiology and Biochemistry
Assuntos:	AT1R Mechanical stress Angiotensin II Sensitive sites Cardiac hypertrophy
Acesso em linha:	http://www.karger.com/Article/FullText/430337
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