Expression and Display of Glycoengineered Antibodies and Antibody Fragments with an Engineered Yeast Strain

Interactions with cell surface receptors enhance the therapeutic properties of many important antibodies, including the low-affinity Fc γ Receptors (FcγRs). These interactions require proper processing of the immunoglobulin G Fc <i>N</i>-glycan, and eliminating the <i>N</i>-glycan abolishes binding,...

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Prif Awduron:	Anjali Shenoy, Srisaimaneesh Yalamanchili, Alexander R. Davis, Adam W. Barb
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2021-09-01
Cyfres:	Antibodies
Pynciau:	human immunoglobulin 1 (hIgG1) human Fc gamma receptor IIIa (FcγIIIa) EndoS2 truncated <i>N</i>-glycan
Mynediad Ar-lein:	https://www.mdpi.com/2073-4468/10/4/38
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!