Formulation of ciprofloxacin-loaded oral self-emulsifying drug delivery system to improve the pharmacokinetics and antibacterial activity

This study aims to increase the aqueous solubility of ciprofloxacin (CPN) to improve oral bioavailability. This was carried out by formulating a stable formulation of the Self-Emulsifying Drug Delivery System (SEDDS) using various ratios of lipid/oil, surfactant, and co-surfactant. A pseudo-ternary...

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Hlavní autoři:	Asghar Ali Asghar, Muhammad Akhlaq, Aamir Jalil, Abul Kalam Azad, Junaid Asghar, Muhammad Adeel, Ghadeer M. Albadrani, Amin A. Al-Doaiss, Mohamed Kamel, Ahmed E. Altyar, Mohamed M. Abdel-Daim
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-10-01
Edice:	Frontiers in Pharmacology
Témata:	ciprofloxacin pseudo-ternary phase diagram self-emulsifying drug delivery system oral bioavailability solubility
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2022.967106/full
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