Oxidative stress suppression contributes to antiseizure action of axitinib and rapamycin in pentylenetetrazol-induced kindling
Rapamycin and axitinib block different kinases in signaling pathways such as PI3K-Akt-mTOR and BDNF-TrkB, respectively. Both have antiseizure and antioxidative actions, which justify studying the combined effects of these drugs upon seizures and oxidative stress in the chronic model of epilepsy. The...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2021-04-01
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| Serie: | The Ukrainian Biochemical Journal |
| Soggetti: | |
| Accesso online: | http://ukrbiochemjournal.org/wp-content/uploads/2021/05/Poshyvak_2_21.pdf |
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