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Flurochloridone-induced apoptosis via IRE1α-JNK signaling pathway in mice testicular cells and TM4 cells

BackgroundFlurochloridone (FLC) can induce apoptosis in Sertoli cells, but the specific mechanism remains unknown.ObjectiveTo investigate the testicular cell apoptosis in mice as well as apoptosis and activation of endoplasmic reticulum stress in TM4 cell line induced by FLC through in vivo and in v...

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Principais autores: Fen ZHANG, Rui LI, Shuqi ZHAO, Yanna WANG, Zhijing NI, Xiuli CHANG, Zhijun ZHOU
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Committee of Journal of Environmental and Occupational Medicine 2022-09-01
coleção:环境与职业医学
Assuntos:
flurochloridone
testis
tm4 cell
apoptosis
endoplasmic reticulum stress
unfolded protein response
Acesso em linha:http://www.jeom.org/article/cn/10.11836/JEOM22098
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