Glutamate-bound NMDARs arising from in vivo-like network activity extend spatio-temporal integration in a L5 cortical pyramidal cell model.
In vivo, cortical pyramidal cells are bombarded by asynchronous synaptic input arising from ongoing network activity. However, little is known about how such 'background' synaptic input interacts with nonlinear dendritic mechanisms. We have modified an existing model of a layer 5 (L5) pyramidal cell...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science (PLoS)
2014-04-01
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| سلاسل: | PLoS Computational Biology |
| الوصول للمادة أونلاين: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003590&type=printable |
| الوسوم: |
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