Cellular senescence in cancer immunology and potential therapeutic strategy

Cellular senescence represents a state of stable, often irreversible cell cycle arrest. Unlike apoptosis, senescent cells (SCs) remain metabolically active and engage in robust secretory activity, most notably through the senescence-associated secretory phenotype (SASP). The SASP exerts profound and...

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Principais autores:	Xiao-Dan Qian, Li-De Tao, Li-Hong Zhang, An-Lai Ji, Lei Wang, Muhammad Mudasar Iqbal, Yi Luo
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-04-01
Series:	Frontiers in Oncology
Assuntos:	cellular senescence senescence-associated secretory phenotype immunosuppressive immune evasion immunotherapy
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1737652/full
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