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Validation of p53 Immunohistochemistry (PAb240 Clone) in Canine Tumors with Next-Generation Sequencing (NGS) Analysis

In human medicine, p53 immunohistochemistry (IHC) is a common method that is used for the identification of tumors with <i>TP53</i> mutations. In veterinary medicine, several studies have performed IHC for p53 in canine tumors, but it is not known how well it actually predicts the mutation. The aim...

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Principais autores: Barbara Brunetti, Dario de Biase, Giulia Dellapina, Luisa Vera Muscatello, Francesco Ingravalle, Giorgia Tura, Barbara Bacci
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-03-01
Serier:Animals
Fag:
accuracy
canine tumors
immunohistochemistry
NGS
p53
sensitivity
Online adgang:https://www.mdpi.com/2076-2615/13/5/899
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