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Complement-mediated HUS revisited: evolving insights into pathophysiology, diagnosis, and treatment

Complement-mediated hemolytic uremic syndrome (CM-HUS), commonly referred to as atypical HUS, is a rare thrombotic microangiopathy caused by uncontrolled activation of the alternative complement pathway, typically triggered by a “two-hit” mechanism. It is characterized by microangiopathic hemolytic...

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Principais autores: Ruah Alyamany, Ann M Moyer, Maria Alice V. Willrich, Meera Sridharan
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-01-01
Series:Frontiers in Immunology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1621317/full
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