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Comparative Genomics and Metabolomics in the Genus Nocardia

ABSTRACT Using automated genome analysis tools, it is often unclear to what degree genetic variability in homologous biosynthetic pathways relates to structural variation. This hampers strain prioritization and compound identification and can lead to overinterpretation of chemical diversity. Here, w...

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Principais autores: Daniel Männle, Shaun M. K. McKinnie, Shrikant S. Mantri, Katharina Steinke, Zeyin Lu, Bradley S. Moore, Nadine Ziemert, Leonard Kaysser
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020-06-01
Serier:mSystems
Fag:
Nocardia
biosynthetic gene cluster
genome mining
genomics
metabolomics
natural products
Online adgang:https://journals.asm.org/doi/10.1128/msystems.00125-20
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