Código QR (código de barras bidimensional)

A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation

In eukaryotic cells, stressors reprogram the cellular proteome by activating the integrated stress response (ISR). In its canonical form, stress-sensing kinases phosphorylate the eukaryotic translation initiation factor eIF2 (eIF2-P), which ultimately leads to reduced levels of ternary complex requi...

תיאור מלא

שמור ב:
Principais autores: Morgane Boone, Lan Wang, Rosalie E Lawrence, Adam Frost, Peter Walter, Michael Schoof
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications Ltd 2022-04-01
סדרה:eLife
נושאים:
eIF2B
ISR
ISRIB
eIF2
allostery
גישה מקוונת:https://elifesciences.org/articles/76171
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים