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De Novo Variants Found in Three Distinct Schizophrenia Populations Hit a Common Core Gene Network Related to Microtubule and Actin Cytoskeleton Gene Ontology Classes

Schizophrenia (SZ) is a heterogeneous and debilitating psychiatric disorder with a strong genetic component. To elucidate functional networks perturbed in schizophrenia, we analysed a large dataset of whole-genome studies that identified SNVs, CNVs, and a multi-stage schizophrenia genome-wide associ...

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Principais autores: Yann Loe-Mie, Christine Plançon, Caroline Dubertret, Takeo Yoshikawa, Binnaz Yalcin, Stephan C. Collins, Anne Boland, Jean-François Deleuze, Philip Gorwood, Dalila Benmessaoud, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-02-01
Serier:Life
Fag:
schizophrenia trios
cohorts
mutation
gene ontology
cytoskeleton
microtubule
Online adgang:https://www.mdpi.com/2075-1729/14/2/244
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