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HIF2α-induced lysyl oxidase safeguards successful pregnancy by remodelling collagens at the feto-maternal interface

Abstract During the initial stage of gestation, precise constructions of the microenvironment at the feto-maternal interface are critical for successful embryonic development to term. It consists of the fetal placenta and the maternal decidua, contributing to favorable pregnancy outcomes and long-te...

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Bibliografische Detailangaben
Hauptverfasser: Shizu Aikawa, Ryoko Shimizu-Hirota, Akihiko Sakashita, Xueting He, Daiki Hiratsuka, Chihiro Ishizawa, Rei Iida, Yamato Fukui, Takehiro Hiraoka, Mitsunori Matsuo, Norihiko Takeda, Masahito Ikawa, Yutaka Osuga, Yasushi Hirota
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2026-03-01
Schriftenreihe:Cell Death and Disease
Online-Zugang:https://doi.org/10.1038/s41419-026-08485-8
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