Establishment and validation of an alternative automated synthesis of [68Ga]Ga-DOTA-Siglec-9 in an independent laboratory for clinical use

Abstract Background Siglec-9, a member of the Siglec family of receptors, plays a crucial role in modulating immune cell trafficking and inflammation, with significant clinical implications. It is predominantly expressed on immune cells such as neutrophils, monocytes, and dendritic cells –key compon...

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Hauptverfasser:	Silvia Migliari, Alessandra Guercio, Anna Gagliardi, Roberta Giaccari, Stefano Bruno, Anne Roivainen, Sarita Forsback, Giorgio Baldari, Maura Scarlattei, Livia Ruffini
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	SpringerOpen 2025-10-01
Schriftenreihe:	EJNMMI Radiopharmacy and Chemistry
Schlagworte:	[68Ga]Ga-radiopharmaceuticals [68Ga]Ga-DOTA-Siglec-9 VAP-1 PET imaging
Online-Zugang:	https://doi.org/10.1186/s41181-025-00396-x
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