Hair follicle gene expression profiling in the SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS)

Abstract Background Transcriptomic analysis is common in large cohort studies but is generally restricted to cells in blood, which limits inferences about organs of interest, and direct organ sampling is mostly infeasible in large cohorts. New techniques for RNA-seq from noninvasive biosamples may p...

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Principais autores:	Kristina L. Buschur, Molly Martorella, Renee Garcia-Flores, Benjamin M. Smith, Marcello Ziosi, Igor Barjaktarevic, Eugene R. Bleecker, Stephanie A. Christenson, Alejandro P. Comellas, Gerard J. Criner, Mark T. Dransfield, Nadia N. Hansel, Robert J. Kaner, Jerry A. Krishnan, Deborah A. Meyers, Elizabeth C. Oelsner, Victor E. Ortega, Robert Paine, Prescott G. Woodruff, R. Graham Barr, Tuuli Lappalainen
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-12-01
Series:	BMC Medical Genomics
Assuntos:	Hair follicle RNA-seq Lung
Acceso en liña:	https://doi.org/10.1186/s12920-025-02270-w
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