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Large-scale survey for novel genotypes of <it>Plasmodium falciparum </it>chloroquine-resistance gene <it>pfcrt</it>

<p>Abstract</p> <p>Background</p> <p>In <it>Plasmodium falciparum</it>, resistance to chloroquine (CQ) is conferred by a K to T mutation at amino acid position 76 (K76T) in the <it>P. falciparum </it>CQ transporter (PfCRT). To date, at least 15 <it>pfcrt </it>genotypes, which are represented by comb...

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Hlavní autoři: Takahashi Nobuyuki, Tanabe Kazuyuki, Tsukahara Takahiro, Dzodzomenyo Mawuli, Dysoley Lek, Khamlome Boualam, Sattabongkot Jetsumon, Nakamura Masatoshi, Sakurai Miki, Kobayashi Jun, Kaneko Akira, Endo Hiroyoshi, Hombhanje Francis, Tsuboi Takafumi, Mita Toshihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2012-03-01
Edice:Malaria Journal
Témata:
<it>Plasmodium falciparum</it>
Chloroquine resistance
<it>pfcrt</it>
Microsatellite
Haplotype network
Evolution
On-line přístup:http://www.malariajournal.com/content/11/1/92
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