Associating cancer-related RNA structure disrupting SNPs in LincRNAs to function

Abstract Background Long intergenic non-coding RNAs (lincRNAs) and single nucleotide polymorphisms (SNPs) have been associated with cancers for years, yet the molecular mechanism is mostly unclear. The secondary structure of lincRNAs is often crucial for their biological function but can be disrupte...

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Detalhes bibliográficos

Principais autores:	Xueer Han, Christian Anthon, Adrian Sven Geissler, Radhakrishnan Sabarinathan, Stefan Ernst Seemann, Jakob Hull Havgaard, Jan Gorodkin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	BMC Genomics
Assuntos:	Long non-coding RNA Single nucleotide polymorphism RNA secondary structure Human cancer Structural disruption RNA binding protein
Acesso em linha:	https://doi.org/10.1186/s12864-025-12226-0
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