Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells

The nuclear receptor Pparg regulates urothelial differentiation in vitro but its role in healthy urothelium is unclear. Here, the authors show that PPAR gamma mediates urothelial development during both homeostasis (via mitochondrial function) and following infection, via an inflammatory response.

Podrobná bibliografie

Hlavní autoři:	Chang Liu, Tiffany Tate, Ekatherina Batourina, Steven T. Truschel, Steven Potter, Mike Adam, Tina Xiang, Martin Picard, Maia Reiley, Kerry Schneider, Manuel Tamargo, Chao Lu, Xiao Chen, Jing He, Hyunwoo Kim, Cathy Lee Mendelsohn
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2019-10-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-019-12332-0
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!