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Isolated anti-Ro52 identifies a severe subset of Sjögren’s syndrome patients

IntroductionSerum autoantibodies targeting the SSA/Ro proteins are a key component of the classification criteria for the diagnosis of Sjögren’s syndrome (SS). Most patients' serum reacts with both Ro60 and Ro52 proteins. Here we compare the molecular and clinical characteristics of patients diagnos...

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Principais autores: Adrian Y. S. Lee, Trishni Putty, Ming-Wei Lin, Sanjay Swaminathan, Dan Suan, Tim Chataway, Rogier M. Thurlings, Tom P. Gordon, Jing Jing Wang, Joanne H. Reed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-03-01
coleção:Frontiers in Immunology
Assuntos:
anti-Ro52/TRIM21
autoantibodies
cryoglobulinaemia
rheumatoid factor, Ro/La
Sjögren’s syndrome
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1115548/full
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