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Genetic evidence for a periplasmic protein as a third component for a subset of NtrYX family two-component systems

ABSTRACT PlrSR, a member of the NtrYX family of two-component regulatory systems (TCSs), is required for the classical bordetellae, including the causative agent of whooping cough, Bordetella pertussis, to persist in the lower respiratory tract. The plrSR genes are in the middle of a six-gene cluste...

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Huvudupphov: Alexa R. Wolber, Liliana S. McKay, Richard M. Johnson, Zain T. Hameed, Katlyn B. Mote, Steven M. Julio, Peggy A. Cotter
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology 2026-03-01
Serie:Journal of Bacteriology
Ämnen:
proteobacteria
NtrYX
Bordetella
gene regulation
two-component regulatory system
Länkar:https://journals.asm.org/doi/10.1128/jb.00521-25
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