SELENOK-dependent CD36 palmitoylation regulates microglial functions and Aβ phagocytosis

Amyloid-beta (Aβ) is a key factor in the onset and progression of Alzheimer's disease (AD). Selenium (Se) compounds show promise in AD treatment. Here, we revealed that selenoprotein K (SELENOK), a selenoprotein involved in immune regulation and potentially related to AD pathology, plays a critical...

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Hlavní autoři:	Pei Ouyang, Zhiyu Cai, Jiaying Peng, Shujing Lin, Xiaochun Chen, Changbin Chen, Ziqi Feng, Lin Wang, Guoli Song, Zhonghao Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-04-01
Edice:	Redox Biology
Témata:	Selenoprotein K Amyloid-beta Alzheimer's disease CD36 palmitoylation Microglial phagocytosis
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2213231724000405
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