Identification of key genes and pathways revealing the central regulatory mechanism of brain-derived glucagon-like peptide-1 on obesity using bioinformatics analysis

ObjectiveCentral glucagon-like peptide-1 (GLP-1) is a target in treating obesity due to its effect on suppressing appetite, but the possible downstream key genes that GLP-1 regulated have not been studied in depth. This study intends to screen out the downstream feeding regulation genes of central G...

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Hauptverfasser:	Yuwei Shao, Jun Tian, Yanan Yang, Yan Hu, Ye Zhu, Qing Shu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2022-08-01
Schriftenreihe:	Frontiers in Neuroscience
Schlagworte:	glucagon-like peptide-1 (GLP-1) appetite obesity bioinformatics chemical genetics
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fnins.2022.931161/full
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