In silico design of a novel antigen based on safe epitopes of epsilon toxin: avoidance of potential molecular mimicry involved in autoimmune responses

Abstract Background Clostridium perfringens, a bacterium associated with various animal and human diseases, could produce several toxins, such as epsilon toxin (ETX). The economic importance of ETX is related to its ability to cause enterotoxemia in domestic ruminants, which causes sudden death. Thi...

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Hauptverfasser:	Saeed Khalili, Othman Jamal Nassrullah, Yaqdhan Alnomani, Mohammad Reza Rahbar, Abolfazl Jahangiri
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	SpringerOpen 2025-09-01
Schriftenreihe:	Beni-Suef University Journal of Basic and Applied Sciences
Schlagworte:	Epsilon toxin ETX Multiple sclerosis Autoimmune disease Vaccine Molecular mimicry
Online-Zugang:	https://doi.org/10.1186/s43088-025-00685-z
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