IFN-γ and IL-17 elicit synergistic anti-mycobacterial responses by inhibiting coronin-1A retention

Abstract CD4+IFN-γ+IL-17+ T cells and their secreted cytokines play a critical role in the anti-mycobacterial response. However, the underlying synergistic mechanism of IFN-γ and IL-17 is little known. This study demonstrates that the downregulation of coronin-1A retention on the phagosome is a syne...

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Principais autores:	Hye-Soo Park, Thuy An Pham, ZongYou Jiang, Seunga Choi, Yong Woo Back, In-Taek Jang, Ki Won Shin, Yeo-Jin Son, Han-Gyu Choi, Hwa-Jung Kim
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-12-01
Serija:	Communications Biology
Online dostop:	https://doi.org/10.1038/s42003-025-09277-0
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