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Synthesis of Cefuroxime antibiotic precursor:[(6R,7R)-7-[2-furanyl-(z)-2-methoxyimino] acetamido-3-hydroxymethyl-3-cephem-4-carboxylic acid

Synthesis of 3-hydroxy cefuroxime antibiotic has been reported using 7-aminocephalosporanic acid (7-ACA) and 2-furanyl-Z-2-methoxy iminoacetic acid salt. Synthesis of this compound was carried out in three steps with good yield omitting acetyl group or in fact hydrolysis of 7-aminocephalosporanic ac...

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Autori principali: Yaghoub Sarrafi, Kamal Alimohammadi, Khadijeh Alipour
Natura: Artigo
Lingua:Inglês
Pubblicazione: Semnan University 2009-11-01
Serie:شیمی کاربردی روز
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Accesso online:https://chemistry.semnan.ac.ir/article_564_d23f7497922df00db1ee84991cd17290.pdf
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