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Sexual dimorphism in colon is mediated by an androgen-IL33+ stromal cell axis

Abstract Background Males and females exhibit pronounced disparity in the epidemiology, clinical progression, and therapeutic outcomes of colonic diseases, but the underlying mechanisms that regulate sexual dimorphism of colon remain poorly understood. Results We determined the colon as a pivotal an...

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Hauptverfasser: Haoyu Wang, Baowei Jing, Juan Zou, Tian Lan, Mengxin Hu, Lan Lin, Hanhua Cheng, Rongjia Zhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-10-01
Schriftenreihe:Cell & Bioscience
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Online-Zugang:https://doi.org/10.1186/s13578-025-01493-9
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