Prediction accuracy of regulatory elements from sequence varies by functional sequencing technique

IntroductionVarious sequencing based approaches are used to identify and characterize the activities of cis-regulatory elements in a genome-wide fashion. Some of these techniques rely on indirect markers such as histone modifications (ChIP-seq with histone antibodies) or chromatin accessibility (ATA...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Ronald J. Nowling, Kimani Njoya, John G. Peters, Michelle M. Riehle
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2023-08-01
Цуврал:	Frontiers in Cellular and Infection Microbiology
Нөхцлүүд:	enhancers functional sequencing machine learning sequence models DNase-seq STARR-seq
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1182567/full
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