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SMAD7 regulates the canonical Wnt signaling through TGF-β cascade crosstalk and SMAD7/β-CATENIN transcription factor complex formation during tooth regeneration

Abstract Tooth morphogenesis is orchestrated by a complex interplay of signaling pathways and transcription factors that control cell proliferation, apoptosis, and differentiation, with the Wnt/β-catenin signaling pathway playing a pivotal role. However, the comprehensive regulatory mechanisms of Wn...

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Bibliografiske detaljer
Principais autores: Qiuyu Chen, Zhi Liu, Bohuai Zhou, Cheng Liang, Yiping Chen, Weidong Tian, Tian Chen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2026-01-01
Serier:International Journal of Oral Science
Online adgang:https://doi.org/10.1038/s41368-025-00393-5
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