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The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice

Abstract Background The role of PPARα in gene regulation in mouse liver is well characterized. However, less is known about the role of PPARα in human liver. The aim of the present study was to better characterize the impact of PPARα activation on gene regulation in human liver. To that end, chimeri...

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Principais autores: Montserrat A. de la Rosa Rodriguez, Go Sugahara, Guido J. E. J. Hooiveld, Yuji Ishida, Chise Tateno, Sander Kersten
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-06-01
coleção:BMC Genomics
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Acesso em linha:http://link.springer.com/article/10.1186/s12864-018-4834-3
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