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G protein-coupled receptor signaling in osteogenic bone mesenchymal stem/stromal cells

Skeletal integrity is maintained throughout the lifespan by tightly coordinated actions of cells in the bone microenvironment. In healthy bone, matrix resorption by osteoclasts is balanced by new matrix synthesis by osteoblasts. Tipping this balance to favor resorption depletes bone mineral and disr...

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Hlavní autoři: Trevor J. Wolfe, Samantha R. Weaver
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-06-01
Edice:Frontiers in Cell and Developmental Biology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fcell.2026.1795445/full
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