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Particulate matter from car exhaust alters function of human iPSC-derived microglia

Abstract Background Air pollution is recognized as an emerging environmental risk factor for neurological diseases. Large-scale epidemiological studies associate traffic-related particulate matter (PM) with impaired cognitive functions and increased incidence of neurodegenerative diseases such as Al...

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Principais autores: Henna Jäntti, Steffi Jonk, Mireia Gómez Budia, Sohvi Ohtonen, Ilkka Fagerlund, Mohammad Feroze Fazaludeen, Päivi Aakko-Saksa, Alice Pebay, Šárka Lehtonen, Jari Koistinaho, Katja M. Kanninen, Pasi I. Jalava, Tarja Malm, Paula Korhonen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-02-01
Serier:Particle and Fibre Toxicology
Fag:
Microglia
Particulate matter
Traffic-related
iPSC
iPSC-microglia
Neuroinflammation
Online adgang:https://doi.org/10.1186/s12989-024-00564-y
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