Aglianico Grape Pomace Extract Reduces Cardiac Pacemaker Activity by Decreasing Hyperpolarization-Activated Current Density Independently of cAMP Signaling

Grape pomace extract (GPE) from <i>Vitis vinifera</i> L. cv. Aglianico is rich in polyphenols with recognized cardioprotective properties, yet its direct electrophysiological effects on spontaneous cardiac activity have not been previously investigated. Here, we examined the chronotropic effects of...

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मुख्य लेखकों:	Roberta De Zio, Maira Certini, Eugenia Pignataro, Daniela Russo, Simona Ida Scorza, Serena Milano, Giuseppe Procino, René Massimiliano Marsano, Maria Svelto, Isabella Maiellaro, Luigi Milella, Monica Carmosino, Andrea Gerbino
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	MDPI AG 2026-05-01
श्रृंखला:	Life
विषय:	grape pomace extract funny current HCN channels cardiac pacemaker diastolic depolarization polyphenols
ऑनलाइन पहुंच:	https://www.mdpi.com/2075-1729/16/5/786
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