CHD4 Orchestrates Chromatin Remodeling to Activate the c‐Myc Signaling Pathway in Cancer Pathogenesis

ABSTRACT Chromatin abnormalities are a hallmark of cancer, but the role of the chromatin remodeler CHD4 in multiple myeloma (MM) remains unclear. This study aims to elucidate how CHD4 drives MM progression and to explore targeted therapeutic strategies. Using CHD4 overexpression and knockdown models...

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Auteurs principaux:	Pinggang Ding, Yuhao Cao, Zihao Liu, Jingru Xie, Lingling Liu, Shanliang Sun, Xichao Yu, Zhendong Deng, Zhimin Fan, Ye Yang, Chunyan Gu
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2026-06-01
Collection:	MedComm – Oncology
Sujets:	CHD4 chromatin accessibility c‐Myc G‐quadruplex liquid‐liquid phase separation multiple myeloma
Accès en ligne:	https://doi.org/10.1002/mog2.70073
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