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Thymoquinone ameliorate oxidative stress, GABAergic neuronal depletion and memory impairment through Nrf2/ARE signaling pathway in the dentate gyrus following cypermethrin administration

Abstract Background Exposure to chemical toxins, including insecticides, harms bodily organs like the brain. This study examined the neuroprotective of thymoquinone on the cypermethrin’s harmful effects on the histoarchitecture of the dentate gyrus and motor deficit in the dentate gyrus. Methods For...

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Principais autores: Abubakar Lekan Imam, Akeem Ayodeji Okesina, Fatimo Ajoke Sulaimon, Aminu Imam, Ruqayyah Yetunde Ibiyeye, Lukuman Aboyeji Oyewole, Sikiru Abayomi Biliaminu, Monsur Shehu, Abdulhameed Oluwatomi Alli, Oluwatosin Olasheu Omoola, Salihu Moyosore Ajao
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2024-09-01
סדרה:BMC Neuroscience
נושאים:
Cypermethrin
Thymoquinone
Cresyl fast violet
GABBAergic interneuron
Dentate gyrus
גישה מקוונת:https://doi.org/10.1186/s12868-024-00896-7
תגים: הוספת תג
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