Critical Role for Very-Long Chain Sphingolipids in Invariant Natural Killer T Cell Development and Homeostasis

The role of sphingolipids (SLs) in the immune system has come under increasing scrutiny recently due to the emerging contributions that these important membrane components play in regulating a variety of immunological processes. The acyl chain length of SLs appears particularly critical in determini...

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Detalhes bibliográficos

Principais autores:	Ashish Saroha, Yael Pewzner-Jung, Natalia S. Ferreira, Piyush Sharma, Youenn Jouan, Samuel L. Kelly, Ester Feldmesser, Alfred H. Merrill, François Trottein, Christophe Paget, Karl S. Lang, Anthony H. Futerman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-11-01
coleção:	Frontiers in Immunology
Assuntos:	very-long chain ceramides glycosphingolipids invariant natural killer T cells ceramide synthase 2 lymphocytic choriomeningitis virus liver
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01386/full
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