Study on the Mechanism of <i>Paeoniflorin</i>, an Active Component of <i>Paeonia lactiflora Pall.</i>, in Improving Skin Pigmentation by Inhibiting the TNF-α Signaling Pathway

<b>Background/Objectives</b>: This article employs both in vivo and in vitro experiments. <b>Methods</b>: The core targets and key pathways of <i>Paeoniflorin</i> were predicted using a PPI network analysis, GO analysis, and KEGG analysis. Subsequently, molecular docking analysis and molecular simul...

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Autori principali:	Kela Yin, Song Wang, Weina Wang, Tingting Liu, Dejun Qi, Wei Wang, Marwan M. A. Rashed, Hong Duan, Chenghui He, Mengxiao Zhang, Hao Liu, Kefeng Zhai
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2026-03-01
Serie:	Pharmaceuticals
Soggetti:	<i>Paeoniflorin</i> melanin production TNF-α signaling pathway network pharmacology molecular docking regulation
Accesso online:	https://www.mdpi.com/1424-8247/19/3/443
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