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PNPase is involved in the coordination of mRNA degradation and expression in stationary phase cells of Escherichia coli

Abstract Background Exoribonucleases are crucial for RNA degradation in Escherichia coli but the roles of RNase R and PNPase and their potential overlap in stationary phase are not well characterized. Here, we used a genome-wide approach to determine how RNase R and PNPase affect the mRNA half-lives...

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Hlavní autoři: Clémentine Dressaire, Vânia Pobre, Sandrine Laguerre, Laurence Girbal, Cecilia Maria Arraiano, Muriel Cocaign-Bousquet
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-11-01
Edice:BMC Genomics
Témata:
RNA decay
PNPase
RNase R
E. coli
Transcriptome
Gene expression regulation
On-line přístup:http://link.springer.com/article/10.1186/s12864-018-5259-8
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